Volume EM: a quiet revolution takes shape

Lucy M. Collinson*, Carles Bosch, Anwen Bullen, Jemima J. Burden, Raffaella Carzaniga, Cheng Cheng, Michele C. Darrow, Georgina Fletcher, Errin Johnson, Kedar Narayan, Christopher J. Peddie, Martyn Winn, Charles Wood, Ardan Patwardhan, Gerard J. Kleywegt, Paul Verkade*

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

38 Citations (Scopus)
66 Downloads (Pure)

Abstract

Volume electron microscopy (vEM) is a group of techniques that reveal the 3D ultrastructure of cells and tissues through continuous depths of at least 1 micrometer. A burgeoning grassroots community effort is fast building the profile and revealing the impact of vEM technology in the life sciences and clinical research.
Original languageEnglish
Pages (from-to)777-782
Number of pages6
JournalNature Methods
Volume20
Issue number6
DOIs
Publication statusPublished - 19 Apr 2023

Bibliographical note

Funding Information:
The authors acknowledge the work and dedication of the volunteers from the vEM community who have contributed to the vEM working groups over the past three years. A list of working group members can be found on the vEM community website. The work of L.M.C., R.C. and C.J.P. was supported by the Francis Crick Institute, which receives its core funding from Cancer Research UK (CC0199), the UK Medical Research Council (CC0199) and the Wellcome Trust (CC0199). G.F. acknowledges funding from the BBSRC (BB/S018689/1) and the Royal Microscopical Society. A.P. and G.J.K. acknowledge funding from the Medical Research Council (MRC) and the Biotechnology and Biological Sciences Research Council (BBSRC) (MR/L007835/1 and MR/P019544/1) as well as the Wellcome Trust (221371/Z/20/Z). K.N. acknowledges that this project has been funded in whole or in part with Federal funds from the National Cancer Institute, National Institutes of Health, under contract no. 75N91019D00024. The content of this publication does not necessarily reflect the views or policies of the Department of Health and Human Services, nor does mention of trade names, commercial products or organizations imply endorsement by the US Government.

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