Vulnerability to malaria, tuberculosis, and HIV/AIDS infection and disease. Part 1: determinants operating at individual and household level

Imelda Bates, Caroline Fenton, Janet Gruber, David Lalloo, Antonieta Medina Lara, S Bertel Squire, Sally Theobald, Rachael Thomson, Rachel Tolhurst

Research output: Contribution to journalArticle (Academic Journal)peer-review

189 Citations (Scopus)

Abstract

A high burden of malaria, tuberculosis, and HIV infection contributes to national and individual poverty. We have reviewed a broad range of evidence detailing factors at individual, household, and community levels that influence vulnerability to malaria, tuberculosis, and HIV infection and used this evidence to identify strategies that could improve resilience to these diseases. This first part of the review explores the concept of vulnerability to infectious diseases and examines how age, sex, and genetics can influence the biological response to malaria, tuberculosis, and HIV infection. We highlight factors that influence processes such as poverty, livelihoods, gender discrepancies, and knowledge acquisition and provide examples of how approaches to altering these processes may have a simultaneous effect on all three diseases.

Original languageEnglish
Pages (from-to)267-77
Number of pages11
JournalLancet Infectious Diseases
Volume4
Issue number5
DOIs
Publication statusPublished - May 2004

Keywords

  • Communicable Disease Control
  • Communicable Diseases
  • HIV Infections
  • Humans
  • Malaria
  • Poverty
  • Socioeconomic Factors
  • Tuberculosis
  • World Health

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