Abstract
Diffusion coefficients of water have been measured in the fingers of humans by magnetic resonance imaging. It was found that the measured diffusion coefficients increased with subject age in certain regions of the finger but that these regions differed between males and females. The observation of an increased diffusion coefficient with age appears to be inconsistent with a direct-hydration model and possible explanations are given using other models. It is conjectured that the measured diffusion coefficient of water increases with age as a result of structural changes to proteins.
Original language | English |
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Pages (from-to) | 873-879 |
Number of pages | 7 |
Journal | Magnetic Resonance Imaging |
Volume | 12 |
Issue number | 6 |
DOIs | |
Publication status | Published - 1994 |
Keywords
- Aging
- Cellular water
- Compartmentalisation
- Diffusion coefficient
- Direct hydration
- Finger
- Glycosylation
- Magnetic resonance imaging
- Obstruction effect