What factors explain the association between socioeconomic deprivation and reduced likelihood of live-donor kidney transplantation? A questionnaire based pilot case-control study

Pippa Bailey, Charles Tomson, Yoav Ben-Shlomo

Research output: Contribution to journalArticle (Academic Journal)peer-review

4 Citations (Scopus)
249 Downloads (Pure)

Abstract

Objectives
Socioeconomically deprived individuals with renal disease are less likely to receive a live-donor kidney transplant than less deprived individuals. This study aimed to develop and pilot a questionnaire designed to determine what factors explain this association.

Design
Questionnaire development and a pilot case-control study. Primary aims were to develop and evaluate a questionnaire, assess response rates and to generate data to inform full-scale study design.

Setting
A UK tertiary renal referral hospital and transplant centre. Participants Invited participants comprised 30 live-donor kidney transplant recipients (cases) and 30 deceased donor kidney transplant recipients (controls). Participants were randomly sampled from all adults who had been transplanted at Southmead Hospital, North Bristol NHS Trust between 1/8/2007 and 31/7/13.

Methods
Participants were posted questionnaires accompanied by an invitation letter from the renal consultant responsible for their care, and a patient information leaflet. Non-responders were sent a second questionnaire after 4-6 weeks. Data was extracted from returned questionnaires and entered onto a REDCapTM database.

Results
63% (n=38) of those invited returned questionnaires. 16 (42%) declined to answer the question on income. 58% of participants had not asked any of their potential donors to consider living kidney donation (52% LDKT vs 65% DDKT, p=0.44). There was some evidence of a difference between the R3K-T knowledge score for recipients of LDKTs (Mean 6.7, SD 1.8) and for recipients of DDKTs (Mean 4.9, SD 2.1), p=0.008. Variable distribution for the exposure variables of interest were determined.

Conclusions
Findings from this study will inform a sample size calculation for a full-scale study. The findings of the full-scale case-control study will help us better understand how socioeconomic deprivation is related to the type of transplant an individual receives. This understanding will help us to design and appropriately tailor an intervention to reduce inequitable access to live-donor kidney
transplantation.
Original languageEnglish
Article numbere012132
Number of pages12
JournalBMJ Open
Volume6
Issue number6
Early online date9 Jun 2016
DOIs
Publication statusPublished - Jun 2016

Keywords

  • Live-donor kidney transplantation
  • Socioeconomic inequities
  • Pilot study

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