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What is the evidence for interactions between filaggrin null mutations and environmental exposures in the aetiology of atopic dermatitis? A systematic review

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Original languageEnglish
Number of pages9
JournalBritish Journal of Dermatology
Early online date11 Feb 2020
DOIs
DateAccepted/In press - 2 Dec 2019
DateE-pub ahead of print (current) - 11 Feb 2020

Abstract

Atopic dermatitis (AD), also known as eczema or atopic eczema, is a complex, multifactorial often debilitating disease.1 The prevalence of AD has risen rapidly, suggesting that environmental factors might be responsible for such changes.2 s.3 It is crucial to better understand the aetiology of AD to discover ways to reduce the personal and public health burden.

    Research areas

  • Atopic dermatitis, atopic eczema, filaggrin, FLG, exposure, gene‐environment interaction

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    Rights statement: This is the final published version of the article (version of record). It first appeared online via Wiley at https://doi.org/10.1111/bjd.18778 . Please refer to any applicable terms of use of the publisher.

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    Licence: CC BY

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