Whole-Body MRI Virtual Autopsy Using Diffusion-weighted Imaging With Background Suppression (DWIBS) at 3 T in a Child Succumbing to Chordoma

Savvas Andronikou, Marnie L Kemp, Michelle Meiring

Research output: Contribution to journalArticle (Academic Journal)peer-review

2 Citations (Scopus)

Abstract

BACKGROUND: We report the use of diffusion-weighted imaging with background suppression (DWIBS) in pediatric virtual magnetic resonance imaging (MRI) autopsy of a child who succumbed to chordoma.

CASE DESCRIPTION: A 10-year-old girl who succumbed to relapse of a chordoma underwent whole-body virtual MRI autopsy 12 hours postmortem with short Tau inversion recovery (STIR) and DWIBS on 3 T, which demonstrated the primary mass, local and cardiac invasion, and metastatic disease to the thorax, abdomen, head/neck, and musculoskeletal system.

CONCLUSIONS: Postmortem virtual MRI autopsy including DWIBS successfully demonstrated the transthoracic spread of chordoma and invasion of the heart, resulting in blood-borne metastases. Motion and respiratory artifact were not factors during virtual autopsy using DWIBS on 3 T, making ideal use of this technology.

Original languageEnglish
Pages (from-to)133-136
Number of pages4
JournalJournal of Pediatric Hematology/Oncology
Volume39
Issue number2
DOIs
Publication statusPublished - 1 Mar 2017

Keywords

  • Abdominal Neoplasms
  • Autopsy
  • Bone Neoplasms
  • Child
  • Chordoma
  • Female
  • Head and Neck Neoplasms
  • Heart
  • Humans
  • Magnetic Resonance Imaging
  • Myocardium
  • Neoplasm Invasiveness
  • Neoplasm Metastasis
  • Thoracic Neoplasms
  • User-Computer Interface
  • Case Reports
  • Journal Article

Fingerprint Dive into the research topics of 'Whole-Body MRI Virtual Autopsy Using Diffusion-weighted Imaging With Background Suppression (DWIBS) at 3 T in a Child Succumbing to Chordoma'. Together they form a unique fingerprint.

Cite this