WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

H F Zheng; Jonathan H Tobias; E Duncan; David Evans; J Eriksson; Lavinia Paternoster; LM Yerges-Armstrong; T Lehtimaki; U Bergstrom; M Kahonen; PJ Leo; O Raitakari; M Laaksonen; GC Nicholson; J Viikari; M Ladouceur; LP Lyytikainen; C Medina-Gomez; F Rivadeneira; RL Prince; H Sievanen; WD Leslie; D Mellstrom; JA Eisman; S Moverare-Skrtic; D Goltzman; DA Hanley; G Jones; M U B St. Pourcain; Y Xiao; Nicholas J Timpson; George Davey Smith; IR Reid; Susan M Ring; PN Sambrook; M Karlsson; EM Dennison; John P Kemp; P Danoy; Adrian E Sayers; SG Wilson; M Nethander; E McCloskey; L Vandenput; R Eastell; J Liu; T Spector; BD Mitchell; EA Streeten; R Brommage; U Pettersson-Kymmer; MA Brown; C Ohlsson; JB Richards; M Lorentzon

doi:10.1371/journal.pgen.1002745

WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

H F Zheng, Jonathan H Tobias, E Duncan, David Evans, J Eriksson, Lavinia Paternoster, LM Yerges-Armstrong, T Lehtimaki, U Bergstrom, M Kahonen, PJ Leo, O Raitakari, M Laaksonen, GC Nicholson, J Viikari, M Ladouceur, LP Lyytikainen, C Medina-Gomez, F Rivadeneira, RL PrinceH Sievanen, WD Leslie, D Mellstrom, JA Eisman, S Moverare-Skrtic, D Goltzman, DA Hanley, G Jones, M U B St. Pourcain, Y Xiao, Nicholas J Timpson, George Davey Smith, IR Reid, Susan M Ring, PN Sambrook, M Karlsson, EM Dennison, John P Kemp, P Danoy, Adrian E Sayers, SG Wilson, M Nethander, E McCloskey, L Vandenput, R Eastell, J Liu, T Spector, BD Mitchell, EA Streeten, R Brommage, U Pettersson-Kymmer, MA Brown, C Ohlsson, JB Richards, M Lorentzon

Research output: Contribution to journal › Article (Academic Journal) › peer-review

176 Citations (Scopus)

Original language	English
Article number	E1002745
Journal	PLoS Genetics
Volume	8
Issue number	7
DOIs	https://doi.org/10.1371/journal.pgen.1002745
Publication status	Published - 14 Jul 2012

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10.1371/journal.pgen.1002745

http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1002745

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Zheng, H. F., Tobias, J. H., Duncan, E., Evans, D., Eriksson, J., Paternoster, L., Yerges-Armstrong, LM., Lehtimaki, T., Bergstrom, U., Kahonen, M., Leo, PJ., Raitakari, O., Laaksonen, M., Nicholson, GC., Viikari, J., Ladouceur, M., Lyytikainen, LP., Medina-Gomez, C., Rivadeneira, F., ... Lorentzon, M. (2012). WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. PLoS Genetics, 8(7), [E1002745]. https://doi.org/10.1371/journal.pgen.1002745

Zheng, H F ; Tobias, Jonathan H ; Duncan, E ; Evans, David ; Eriksson, J ; Paternoster, Lavinia ; Yerges-Armstrong, LM ; Lehtimaki, T ; Bergstrom, U ; Kahonen, M ; Leo, PJ ; Raitakari, O ; Laaksonen, M ; Nicholson, GC ; Viikari, J ; Ladouceur, M ; Lyytikainen, LP ; Medina-Gomez, C ; Rivadeneira, F ; Prince, RL ; Sievanen, H ; Leslie, WD ; Mellstrom, D ; Eisman, JA ; Moverare-Skrtic, S ; Goltzman, D ; Hanley, DA ; Jones, G ; St. Pourcain, M U B ; Xiao, Y ; Timpson, Nicholas J ; Davey Smith, George ; Reid, IR ; Ring, Susan M ; Sambrook, PN ; Karlsson, M ; Dennison, EM ; Kemp, John P ; Danoy, P ; Sayers, Adrian E ; Wilson, SG ; Nethander, M ; McCloskey, E ; Vandenput, L ; Eastell, R ; Liu, J ; Spector, T ; Mitchell, BD ; Streeten, EA ; Brommage, R ; Pettersson-Kymmer, U ; Brown, MA ; Ohlsson, C ; Richards, JB ; Lorentzon, M. / WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. In: PLoS Genetics. 2012 ; Vol. 8, No. 7.

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title = "WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk",

author = "Zheng, {H F} and Tobias, {Jonathan H} and E Duncan and David Evans and J Eriksson and Lavinia Paternoster and LM Yerges-Armstrong and T Lehtimaki and U Bergstrom and M Kahonen and PJ Leo and O Raitakari and M Laaksonen and GC Nicholson and J Viikari and M Ladouceur and LP Lyytikainen and C Medina-Gomez and F Rivadeneira and RL Prince and H Sievanen and WD Leslie and D Mellstrom and JA Eisman and S Moverare-Skrtic and D Goltzman and DA Hanley and G Jones and {St. Pourcain}, {M U B} and Y Xiao and Timpson, {Nicholas J} and {Davey Smith}, George and IR Reid and Ring, {Susan M} and PN Sambrook and M Karlsson and EM Dennison and Kemp, {John P} and P Danoy and Sayers, {Adrian E} and SG Wilson and M Nethander and E McCloskey and L Vandenput and R Eastell and J Liu and T Spector and BD Mitchell and EA Streeten and R Brommage and U Pettersson-Kymmer and MA Brown and C Ohlsson and JB Richards and M Lorentzon",

year = "2012",

month = jul,

day = "14",

doi = "10.1371/journal.pgen.1002745",

language = "English",

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journal = "PLoS Genetics",

issn = "1553-7390",

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Zheng, HF, Tobias, JH, Duncan, E, Evans, D, Eriksson, J, Paternoster, L, Yerges-Armstrong, LM, Lehtimaki, T, Bergstrom, U, Kahonen, M, Leo, PJ, Raitakari, O, Laaksonen, M, Nicholson, GC, Viikari, J, Ladouceur, M, Lyytikainen, LP, Medina-Gomez, C, Rivadeneira, F, Prince, RL, Sievanen, H, Leslie, WD, Mellstrom, D, Eisman, JA, Moverare-Skrtic, S, Goltzman, D, Hanley, DA, Jones, G, St. Pourcain, MUB, Xiao, Y, Timpson, NJ , Davey Smith, G, Reid, IR, Ring, SM, Sambrook, PN, Karlsson, M, Dennison, EM, Kemp, JP, Danoy, P, Sayers, AE, Wilson, SG, Nethander, M, McCloskey, E, Vandenput, L, Eastell, R, Liu, J, Spector, T, Mitchell, BD, Streeten, EA, Brommage, R, Pettersson-Kymmer, U, Brown, MA, Ohlsson, C, Richards, JB & Lorentzon, M 2012, 'WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk', PLoS Genetics, vol. 8, no. 7, E1002745. https://doi.org/10.1371/journal.pgen.1002745

WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. / Zheng, H F; Tobias, Jonathan H; Duncan, E; Evans, David; Eriksson, J; Paternoster, Lavinia; Yerges-Armstrong, LM; Lehtimaki, T; Bergstrom, U; Kahonen, M; Leo, PJ; Raitakari, O; Laaksonen, M; Nicholson, GC; Viikari, J; Ladouceur, M; Lyytikainen, LP; Medina-Gomez, C; Rivadeneira, F; Prince, RL; Sievanen, H; Leslie, WD; Mellstrom, D; Eisman, JA; Moverare-Skrtic, S; Goltzman, D; Hanley, DA; Jones, G; St. Pourcain, M U B; Xiao, Y; Timpson, Nicholas J ; Davey Smith, George; Reid, IR; Ring, Susan M; Sambrook, PN; Karlsson, M; Dennison, EM; Kemp, John P; Danoy, P; Sayers, Adrian E; Wilson, SG; Nethander, M; McCloskey, E; Vandenput, L; Eastell, R; Liu, J; Spector, T; Mitchell, BD; Streeten, EA; Brommage, R; Pettersson-Kymmer, U; Brown, MA; Ohlsson, C; Richards, JB; Lorentzon, M.

In: PLoS Genetics, Vol. 8, No. 7, E1002745, 14.07.2012.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

TY - JOUR

T1 - WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

AU - Zheng, H F

AU - Tobias, Jonathan H

AU - Duncan, E

AU - Evans, David

AU - Eriksson, J

AU - Paternoster, Lavinia

AU - Yerges-Armstrong, LM

AU - Lehtimaki, T

AU - Bergstrom, U

AU - Kahonen, M

AU - Leo, PJ

AU - Raitakari, O

AU - Laaksonen, M

AU - Nicholson, GC

AU - Viikari, J

AU - Ladouceur, M

AU - Lyytikainen, LP

AU - Medina-Gomez, C

AU - Rivadeneira, F

AU - Prince, RL

AU - Sievanen, H

AU - Leslie, WD

AU - Mellstrom, D

AU - Eisman, JA

AU - Moverare-Skrtic, S

AU - Goltzman, D

AU - Hanley, DA

AU - Jones, G

AU - St. Pourcain, M U B

AU - Xiao, Y

AU - Timpson, Nicholas J

AU - Davey Smith, George

AU - Reid, IR

AU - Ring, Susan M

AU - Sambrook, PN

AU - Karlsson, M

AU - Dennison, EM

AU - Kemp, John P

AU - Danoy, P

AU - Sayers, Adrian E

AU - Wilson, SG

AU - Nethander, M

AU - McCloskey, E

AU - Vandenput, L

AU - Eastell, R

AU - Liu, J

AU - Spector, T

AU - Mitchell, BD

AU - Streeten, EA

AU - Brommage, R

AU - Pettersson-Kymmer, U

AU - Brown, MA

AU - Ohlsson, C

AU - Richards, JB

AU - Lorentzon, M

PY - 2012/7/14

Y1 - 2012/7/14

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U2 - 10.1371/journal.pgen.1002745

DO - 10.1371/journal.pgen.1002745

M3 - Article (Academic Journal)

C2 - 22792071

AN - SCOPUS:84863888921

VL - 8

JO - PLoS Genetics

JF - PLoS Genetics

SN - 1553-7390

IS - 7

M1 - E1002745

ER -

WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

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WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

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B603 THE EFFECT OF COMMON DISEASE ASSOCIATED GENETIC VARIANTS ON TRANSCRIPTOMIC AND EARLY LIFE PHENOTYPES

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