Research Outputs
- 1 - 25 out of 493 results
Search results
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Confinement and Catalysis within De Novo Designed Peptide Barrels
Petrenas, R., Hawkins, O. A., Jones, J. F., Scott, D. A., Fletcher, J. M., Obst, U., Lombardi, L., Pirro, F., Leggett, G. J., Oliver, T. A. A. & Woolfson, D. N., 29 Jan 2025, In: Journal of the American Chemical Society. 147, 4, p. 3796-3803 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Polymer nanodiscs support the functional extraction of an artificial transmembrane cytochrome
Hardy, B. J., Ford, H. C., Rudin, M., Anderson, J. L. R. & Curnow, P., 1 Jan 2025, In: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1867, 1, 8 p., 184392.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Accelerating Genetic Sensor Development, Scale-up, and Deployment Using Synthetic Biology
Joshi, S., Jenkins, C., Ulaeto, D. & Gorochowski, T. E., 25 Jun 2024, In: BioDesign Research. 6, 0037.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
A de novo designed coiled coil-based switch regulates the microtubule motor kinesin-1
Cross, J. A. A., Dawson, W. M., Shukla, S. R., Weijman, J. F. M. S., Mantell, J. M., Dodding, M. P. & Woolfson, D. N., Jul 2024, In: Nature Chemical Biology. 20, 7, p. 916-923 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
An atlas of protein homo-oligomerization across domains of life
Schweke, H., Pacesa, M., Levin, T., Kumar, P., Duhoo, Y., Dornfeld, L. J., Dubreuil, B., Georgeon, S., A. Goverde, C., Ovchinnikov, S., Woolfson, D. N., Correia, B. E., Dey, S. & Levy, E. D., 6 Feb 2024, In: Cell. 187, 4, p. 999-1010.e15 27 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access24 Citations (Scopus) -
An engineered baculoviral protein and DNA co-delivery system for CRISPR-based mammalian genome editing
Capin, J., Harrison, A., Raele, R. A., Yadav, S. K. N., Baiwir, D., Mazzucchelli, G., Quinton, L., Satchwell, T. J., Toye, A. M., Schaffitzel, C., Berger, I. & Aulicino, F., 12 Apr 2024, In: Nucleic Acids Research. 52, 6, p. 3450-3468 19 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access3 Citations (Scopus) -
Antibiotic Origami: Selective Formation of Spirotetronates in Abyssomicin Biosynthesis
Mbatha, S. Z., Back, C., Devine, A. J., Mulliner, H. M., Johns, S. T., Lewin, H., Cheung, K. A., Zorn, K., Stach, J. E. M., Hayes, M. A., Van der Kamp, M. W., Race, P. R. & Willis, C. L., 12 Aug 2024, (E-pub ahead of print) In: Chemical Science. 15, 34, p. 14009-14015 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Assembling membraneless organelles from de novo designed proteins
Hilditch, A. T., Romanyuk, A., Cross, S. J., Obexer, R., McManus, J. J. & Woolfson, D. N., 1 Jan 2024, In: Nature Chemistry. 16, 1, p. 89-97 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access23 Citations (Scopus)56 Downloads (Pure) -
Building a super-resolution fluorescence cryomicroscope
Last, M. G. F., Voortman, L. M. & Sharp, T. H., 13 Mar 2024, (E-pub ahead of print) In: Methods in Cell Biology. p. 205-222 18 p.Research output: Contribution to journal › Article (Academic Journal)
Open AccessFile31 Downloads (Pure) -
Building tailor-made bioenergetic proteins and circuits from de novo redox proteins
Hardy, B. J., Bungay, E. L., Mellor, C., Curnow, P. & Anderson, J. L. R., 24 Jun 2024, In: Current Opinion in Electrochemistry. 46, 101541.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Computational design of de novo bioenergetic membrane proteins
Hardy, B. J. & Curnow, P., 1 Aug 2024, In: Biochemical Society Transactions. 52, 4, p. 1737–1745 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Data hazards in synthetic biology
Zelenka, N. R., Di Cara, N. H., Sarvaharman, S., Ghataora, J. S., Parmeggiani, F., Nivala, J., Abdallah, Z. S., Marucci, L. & Gorochowski, T. E., 6 Jul 2024, In: Synthetic Biology. 9, 1, 10 p., ysae010.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Delineating redox cooperativity in water-soluble and membrane multiheme cytochromes through protein design
Hardy, B. J., Dubiel, P., Bungay, E. L., Rudin, M., Williams, C., Arthur, C. J., Guberman-Pfeffer, M. J., Sofia Oliveira, A., Curnow, P. & Anderson, J. L. R., 9 Jul 2024, In: Protein Science. 33, 8, e5113.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
Delineation of the Complete Reaction Cycle of a Natural Diels-Alderase
Maschio, L., Back, C., Al Nawah, J., Bowen, J. I., Johns, S. T., Mbatha, S. Z., Han, L.-C., Lees, N. R., Zorn, K., Stach, J. E. M., Hayes, M., Van der Kamp, M. W., Pudney, C. R., Burston, S. G., Willis, C. L. & Race, P. R., 24 Jun 2024, (E-pub ahead of print) In: Chemical Science. 15, 29, p. 11572-11583 12 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
emle-engine: A Flexible Electrostatic Machine Learning Embedding Package for Multiscale Molecular Dynamics Simulations
Zinovjev, K., Hedges, L. O., Montagud Andreu, R., Woods, C., Tuñón, I. & van der Kamp, M. W., 11 Jun 2024, In: Journal of Chemical Theory and Computation. 20, 11, p. 4514-4522 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access5 Citations (Scopus) -
Engineering is evolution: a perspective on design processes to engineer biology
Stock, M., Castle, S. D. & Gorochowski, T. E., 29 Apr 2024, In: Nature Communications. 15, 1, 10 p., 3640.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access5 Citations (Scopus) -
Engineering the ADDobody protein scaffold for generation of high-avidity ADDomer super-binders
Buzas, D., Sun, H., Toelzer, C., Yadav, S. K. N., Borucu, U., Gautam, G., Gupta, K., Bufton, J. C., Capin, J. M., Sessions, R. B., Garzoni, F., Berger, I. & Berger-Schaffitzel, C. H., 9 Jan 2024, In: Structure. 32, 3, p. 342-351.e6Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Exchange, promiscuity, and orthogonality in de novo designed coiled-coil peptide assemblies
Kurgan, K. W., Martin, F. J. O., Dawson, W. M., Brunnock, T., Orr-Ewing, A. J. & Woolfson, D. N., 9 Dec 2024, (E-pub ahead of print) In: Chemical Science.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Fluctuation relations to calculate protein redox potentials from molecular dynamics simulations
Oliveira, A. S. F., Rubio, J., Noble, C. E. M., Anderson, J. L. R., Anders, J. & Mulholland, A. J., 9 Jan 2024, In: Journal of Chemical Theory and Computation. 20, 1, p. 385-395 11 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile3 Citations (Scopus)42 Downloads (Pure) -
Functional Integration of Synthetic Cells into 3D Microfluidic Devices for Artificial Organ-on-Chip Technologies
Hakami, N., Burgstaller, A., Gao, N., Rutz, A., Mann, S. & Staufer, O., 24 May 2024, (E-pub ahead of print) In: Advanced Healthcare Materials. 13, 22, 13 p., 2303334.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
Maturation and Conformational Switching of a De Novo Designed Phase-Separating Polypeptide
Hilditch, A., Romanyuk, A., Hodgson, L. R., Mantell, J. M., Neal, C. R., Verkade, P., Obexer, R. J., Serpell, L. C., McManus, J. & Woolfson, D. N., 17 Apr 2024, In: Journal of the American Chemical Society. 146, 15, p. 10240–10245 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access2 Citations (Scopus) -
Molecular organization of fibroin heavy chain and mechanism of fibre formation in Bombyx mori
Moreno Tortolero, R. O., Davis, S. A., Parmeggiani, F., Luo, J., Holland, C., Serpell, L. C., Skaer, N. J. V. & Walker, R., 29 Jun 2024, In: Communications Biology. 7, 1, 786.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access5 Citations (Scopus) -
Open-endedness in synthetic biology: A route to continual innovation for biological design
Stock, M. & Gorochowski, T. E., 19 Jan 2024, In: Science Advances. 10, 3, 13 p., eadi3621.Research output: Contribution to journal › Review article (Academic Journal) › peer-review
Open Access6 Citations (Scopus) -
Optimization of periodic treatment strategies for bacterial biofilms using an agent-based in silico approach
Blee, J., Gorochowski, T. E. & Hauert, S., 10 Apr 2024, In: Journal of the Royal Society Interface. 21, 213, 15 p., 20240078.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Rationally seeded computational protein design of ɑ-helical barrels
Albanese, K. I., Petrenas, R., Pirro, F., Naudin, E. A., Borucu, U., Dawson, W. M., Scott, D. A., Leggett, G. J., Weiner, O., Oliver, T. A. A. & Woolfson, D. N., 1 Aug 2024, In: Nature Chemical Biology. 20, 8, p. 991-999 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access4 Citations (Scopus)