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Manipulating the water–air interface to drive protein assembly for functional silk-like fibroin fibre production
Moreno-Tortolero, R. O., Michalski, J., Wells, E., Gibb, F., Skaer, N., Walker, R., Serpell, L., Holland, C. & Davis, S. A., 21 Dec 2024, In: Communications Materials. 5, 1, 10 p., 277.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Maturation and Conformational Switching of a De Novo Designed Phase-Separating Polypeptide
Hilditch, A., Romanyuk, A., Hodgson, L. R., Mantell, J. M., Neal, C. R., Verkade, P., Obexer, R. J., Serpell, L. C., McManus, J. & Woolfson, D. N., 17 Apr 2024, In: Journal of the American Chemical Society. 146, 15, p. 10240–10245 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access3 Citations (Scopus) -
Molecular organization of fibroin heavy chain and mechanism of fibre formation in Bombyx mori
Moreno Tortolero, R. O., Davis, S. A., Parmeggiani, F., Luo, J., Holland, C., Serpell, L. C., Skaer, N. J. V. & Walker, R., 29 Jun 2024, In: Communications Biology. 7, 1, 786.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access6 Citations (Scopus) -
Open-endedness in synthetic biology: A route to continual innovation for biological design
Stock, M. & Gorochowski, T. E., 19 Jan 2024, In: Science Advances. 10, 3, 13 p., eadi3621.Research output: Contribution to journal › Review article (Academic Journal) › peer-review
Open Access9 Citations (Scopus) -
Optimization of periodic treatment strategies for bacterial biofilms using an agent-based in silico approach
Blee, J., Gorochowski, T. E. & Hauert, S., 10 Apr 2024, In: Journal of the Royal Society Interface. 21, 213, 15 p., 20240078.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Rationally seeded computational protein design of ɑ-helical barrels
Albanese, K. I., Petrenas, R., Pirro, F., Naudin, E. A., Borucu, U., Dawson, W. M., Scott, D. A., Leggett, G. J., Weiner, O., Oliver, T. A. A. & Woolfson, D. N., 1 Aug 2024, In: Nature Chemical Biology. 20, 8, p. 991-999 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access5 Citations (Scopus) -
Reprogramming macrophages with R848-loaded artificial protocells to modulate skin and skeletal wound healing
López-Cuevas, P., Oates, T. C. L., Tong, Q., McGowan, L. M., Cross, S. J., Xu, C., Zhao, Y., Yin, Z., Toye, A. M., Boussahel, A., Hammond, C. L., Mann, S. & Martin, P., 29 Aug 2024, In: Journal of Cell Science. 137, 16, 16 p., jcs262202.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Selection and characterization of a peptide-based complement modulator targeting C1 of the innate immune system
Hamers, S. M. W. R., Abendstein, L., Boyle, A. L., Jongkees, S. A. K. & Sharp, T. H., 1 Jul 2024, In: RSC chemical biology. 5, 8, p. 787-799 13 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Synthetic Immunology - Building Immunity from the Bottom-Up with Synthetic Cells
Staufer, O., 9 Sept 2024, In: Advanced NanoBiomed Research. 4, 9, 2400037.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access3 Citations (Scopus) -
Transfer learning for cross-context prediction of protein expression from 5’UTR sequence
Gilliot, P.-A. M. A. & Gorochowski, T. E., 22 Jul 2024, In: Nucleic Acids Research. 52, 13, 14 p., e58.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access2 Citations (Scopus) -
Tuning VSV-G Expression Improves Baculovirus Integrity, Stability and Mammalian Cell Transduction Efficiency
Mattioli, M., Raele, R. A., Gautam, G., Borucu, U., Schaffitzel, C., Aulicino, F. & Berger, I., 17 Sept 2024, In: Viruses. 16, 9, 17 p., 1475.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
ADDovenom: Thermostable Protein-Based ADDomer Nanoparticles as New Therapeutics for Snakebite Envenoming
Menzies, S. K., Arinto-Garcia, R., Amorim, F. G., Cardoso, I. A., Abada, C., Crasset, T., Durbesson, F., Edge, R. J., El-Kazzi, P., Hall, S., Redureau, D., Stenner, R., Boldrini-França, J., Sun, H., Roldão, A., Alves, P. M., Harrison, R. A., Vincentelli, R., Berger, I. & Quinton, L. & 2 others, , 28 Nov 2023, In: Toxins. 15, 12, 673.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
Allosteric regulation of a molecular motor through de novo protein design
Cross, J. A. A., Dawson, W. M., Shukla, S. R., Weijman, J. F. M. S., Mantell, J. M., Dodding, M. P. & Woolfson, D. N., 17 Oct 2023, In: bioRxiv.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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An expandable, modular de novo protein platform for precision redox engineering
Hutchins, G. H., Noble, C. E. M., Bunzel, H. A., Williams, C., Dubiel, P., Yadav, S. K. N., Molinaro, P. M., Barringer, R., Blackburn, H., Hardy, B. J., Parnell, A. E., Landau, C., Race, P. R., Oliver, T. A. A., Koder, R. L., Crump, M. P., Schaffitzel, C., Oliveira, A. S. F., Mulholland, A. J. & Anderson, J. L. R., 1 Aug 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 31, e2306046120.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access11 Citations (Scopus) -
An N-terminal alpha-synuclein fragment binds lipid vesicles to modulate lipid-induced aggregation
Meade, R., Allen, S. G., Williams, C., Simon Tang, T. M., Crump, M. P. & Mason, J. M., 20 Sept 2023, In: Cell Reports Physical Science. 4, 9, 15 p., 101563.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access3 Citations (Scopus) -
A Photo-degradable Crosslinker for the Development of Light-responsive Protocell Membranes
Grimes, P. J., Jenkinson-Finch, M. E., Symons, H. E., Briscoe, W. H., Rochat, S., Mann, S. & Gobbo, P., 2 Nov 2023, In: Chemistry – A European Journal. 29, 61, 9 p., e202302058.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access2 Citations (Scopus) -
Autonomic Integration in Nested Protocell Communities
Yin, Z., Gao, N., Xu, C., Li, M. & Mann, S., 12 Jul 2023, In: Journal of the American Chemical Society. 145, 27, p. 14727–14736 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access5 Citations (Scopus) -
Bridging the gap between mechanistic biological models and machine learning surrogates
Gherman, I. M., Marucci, L., Gorochowski, T. E., Abdallah, Z. S., Grierson, C. S. & Pang, W., 20 Apr 2023, In: PLoS Computational Biology. 19, 4, p. e1010988 e1010988.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access18 Citations (Scopus) -
CC+: A Searchable Database of Validated Coiled Coils in PDB Structures and AlphaFold2 Models
Kumar, P., Petrenas, R., Dawson, W. M., Schweke, H., Levy, E. D. & Woolfson, D. N., 28 Sept 2023, (E-pub ahead of print) In: Protein Science. 32, 11, e4789.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access3 Citations (Scopus) -
Cellular production of a de novo membrane cytochrome
Hardy, B. J., Hermosilla, A. M., Chinthapalli, D. K., Robinson, C. V., Anderson, J. L. R. & Curnow, P., 18 Apr 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 16, e2300137120.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access7 Citations (Scopus) -
Computational modelling of diatom silicic acid transporters predicts a conserved fold with implications for their function and evolution
Knight, M. J., Hardy, B. J., Wheeler, G. L. & Curnow, P., 1 Jan 2023, In: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1865, 1, p. 1-9 184056.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile3 Citations (Scopus)74 Downloads (Pure) -
Cryo-EM reveals binding of linoleic acid to SARS-CoV-2 spike glycoprotein, suggesting an antiviral treatment strategy
Toelzer, C., Gupta, K., Berger, I. & Berger-Schaffitzel, C. H., 1 Feb 2023, In: Acta Crystallographica Section D: Structural Biology. 79, 2, p. 111-121 11 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access10 Citations (Scopus) -
Design and Analysis of Massively Parallel Reporter Assays Using FORECAST
Gilliot, P.-A. M. A. & Gorochowski, T. E., 2023, Computational Biology and Machine Learning for Metabolic Engineering and Synthetic Biology. Methods in Molecular Biology. Vol. 2553. p. 41-56 16 p. (Methods in Molecular Biology; vol. 2553).Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book
3 Citations (Scopus) -
Design and Selection of Heterodimerizing Helical Hairpins for Synthetic Biology
Smith, A. J., Naudin, E. A., Edgell, C. L., Baker, E. G., Mylemans, B., FitzPatrick, L., Herman, A., Rice, H. M., Andrews, D., Tigue, N., Woolfson, D. N. & Savery, N. J., 16 Jun 2023, In: Journal of the American Chemical Society. 12, 6, p. 1845-1858 14 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access2 Citations (Scopus) -
Differential sensing with arrays of de novo designed peptide assemblies
Dawson, W. M., Shelley, K. L., Fletcher, J. M., Scott, D. A., Lombardi, L., Rhys, G. G., LaGambina, T. J., Obst, U., Burton, A. J., Cross, J. A., Davies, G., Martin, F. J. O., Wiseman, F. J., Brady, R. L., Tew, D., Wood, C. W. & Woolfson, D. N., 24 Jan 2023, In: Nature Communications. 14, 1, 383.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile18 Citations (Scopus)71 Downloads (Pure)