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De novo design of discrete, stable 310-helix peptide assemblies
Kumar, P., Paterson, N. G., Clayden, J. & Woolfson, D. N., 14 Jul 2022, In: Nature. 607, 7918, p. 387-392 11 p., 607.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile34 Citations (Scopus)152 Downloads (Pure) -
Derivation of A Precise and Consistent Timeline for Antibiotic Development
Stennett, H. L., Back, C. & Race, P. R., 8 Sept 2022, (Accepted/In press) In: Antibiotics. 11, 9, p. 1-12 1237.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile12 Citations (Scopus)266 Downloads (Pure) -
Design and Assembly of Multilevel Transcriptional and Translational Regulators for Stringent Control of Gene Expression
Greco, F. V., Irvine, T. C. T., Grierson, C. S. & Gorochowski, T. E., 2022, Riboregulator Design and Analysis. Methods in Molecular Biology. Vol. 2518.Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book
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Development and evaluation of low-volume tests to detect and characterize antibodies to SARS-CoV-2
Halliday, A., Long, A. E., Baum, H. E., Thomas, A., Shelley, K. L., Oliver, E. H., Gupta, K., Francis, O., Kavanagh Williamson, M., Di Bartolo, N. D., Randell, M. J., Ben Khoud, Y., Kelland, I., Mortimer, G. L. M., Ball, O. E., Plumptre, C., Chandler, M. A., Obst, U., Secchi, M. & Piemonti, L. & 27 others, , 9 Nov 2022, In: Frontiers in Immunology. 13, 20 p., 968317.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile2 Citations (Scopus)106 Downloads (Pure) -
From peptides to proteins: coiled-coil tetramers to single-chain 4-helix bundles
Naudin, E. A., Albanese, K. I., Smith, A. J., Mylemans, B., Baker, E. G., Savery, N. J., Woolfson, D. N. & et, A., 20 Sept 2022, In: Chemical Science. 13, 38, p. 11330-11340 11 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile12 Citations (Scopus)64 Downloads (Pure) -
Highly efficient CRISPR-mediated large DNA docking and multiplexed prime editing using a single baculovirus
Aulicino, F., Pelosse, M., Toelzer, C., Capin, J. M., Meysami, P., Dillingham, M. S., Berger-Schaffitzel, C. H., Saleem, M., Welsh, G. I., Berger, I. & et, A., 8 Jul 2022, (E-pub ahead of print) In: Nucleic Acids Research. 50, 13, p. 7783–7799 17 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile26 Citations (Scopus)140 Downloads (Pure) -
HR-Bac, a toolbox based on homologous recombination for expression, screening and production of multiprotein complexes using the baculovirus expression system
Kolesnikova, O., Zachayus, A., Pichard, S., Osz, J., Rochel, N., Rossolillo, P., Kolb-Cheynel, I., Troffer-Charlier, N., Compe, E., Bensaude, O., Berger, I. & Poterszman, A., 7 Feb 2022, In: Scientific Reports. 12, 1, 12 p., 2030.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile7 Citations (Scopus)68 Downloads (Pure) -
Identification and validation of novel microtubule suppressors with an imidazopyridine scaffold through structure-based virtual screening and docking
Elseginy, S. A., Oliveira, S., Shoemark, D. K. & Sessions, R. B., 18 May 2022, (E-pub ahead of print) In: RSC medicinal chemistry. 13, 8, p. 929-943 15 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile9 Citations (Scopus)63 Downloads (Pure) -
Improving the Robustness of Engineered Bacteria to Nutrient Stress Using Programmed Proteolysis
Szydlo, K., Ignatova, Z. & Gorochowski, T. E., 18 Mar 2022, In: ACS Synthetic Biology. 11, 3, p. 1049-1059 11 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile7 Citations (Scopus)82 Downloads (Pure) -
Lumenal components of cytoplasmic microtubules
Tsuji, C. & Dodding, M. P., 16 Dec 2022, In: Biochemical Society Transactions. 50, 6, p. 1953-1962 10 p.Research output: Contribution to journal › Review article (Academic Journal) › peer-review
Open AccessFile7 Citations (Scopus)89 Downloads (Pure) -
Macrophage Reprogramming with Anti-miR223-Loaded Artificial Protocells Enhances In Vivo Cancer Therapeutic Potential
López-Cuevas, P., Xu, C., Severn, C. E., Oates, T. C. L., Cross, S. J., Toye, A. M., Mann, S. & Martin, P., 19 Dec 2022, In: Advanced Science. 9, 35, 20 p., 2202717.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile5 Citations (Scopus)121 Downloads (Pure) -
Massively parallel characterization of engineered transcript isoforms using direct RNA sequencing
Tarnowski, M. J. & Gorochowski, T. E., 21 Jan 2022, In: Nature Communications. 13, 1, 14 p., 434.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile16 Citations (Scopus)166 Downloads (Pure) -
Molecular architecture of the autoinhibited kinesin-1 lambda particle
Weijman, J. F. M. S., Yadav Kadapalakere, S., Surridge, K. J., Cross, J. A. A., Mantell, J. M., Woolfson, D. N., Berger-Schaffitzel, C. H. & Dodding, M. P., 16 Sept 2022, In: Science Advances.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access10 Citations (Scopus) -
Molecular dynamics of spike variants in the locked conformation: RBD interfaces, fatty acid binding and furin cleavage sites
Shoemark, D. K., Oliveira, A. S. F., Davidson, A. D., Berger, I., Schaffitzel, C. & Mulholland, A. J., 8 May 2022Research output: Other contribution
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Pathogen-sugar interactions revealed by universal saturation transfer analysis
Berger-Schaffitzel, C. H. & Berger, I., 23 Jun 2022, In: Science. 377, 6604Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile27 Citations (Scopus)389 Downloads (Pure) -
Photoswitchable gating of non-equilibrium enzymatic feedback in chemically communicating polymersome nanoreactors
Rifaie-Graham, O., Yeow, J., Najer, A., Wang, R., Sun, R., Zhou, K., Dell, T., Adrianus, C., Thanapongpibul, C., Mann, S., Alaniz, J. R. D. & Stevens, M., 11 Feb 2022Research output: Other contribution
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Programmed Iteration Controls the Assembly of the Nonanoic Acid Side Chain of the Antibiotic Mupirocin
Winter, A. J., Rowe, M. T., Weir, A. N. M., Akter, N., Mbatha, S. Z., Walker, P. D., Williams, C., Song, Z., Race, P. R., Willis, C. L. & Crump, M. P., 5 Dec 2022, In: Angewandte Chemie - International Edition. 61, 50, e202212393.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile5 Citations (Scopus)55 Downloads (Pure) -
Q-learning for real time control of heterogeneous microagent collectives
Rubio Denniss, A., Mateu, L. F., Gorochowski, T. E. & Hauert, S., 2022, Proceedings of the ALIFE 2022: The 2022 Conference on Artificial Life. isal_a_00497Research output: Chapter in Book/Report/Conference proceeding › Conference Contribution (Conference Proceeding)
Open Access -
Signal processing and generation of bioactive nitric oxide in a model prototissue
Liu, S., Zhang, Y., He, X., Li, M., Huang, J., Yang, X., Wang, K., Mann, S. & Liu, J., 6 Sept 2022, In: Nature Communications. 13, 1, 12 p., 5254.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile41 Citations (Scopus)64 Downloads (Pure) -
Spontaneous Membranization in a Silk-Based Coacervate Protocell Model
Yin, Z., Tian, L., Patil, A. J., Li, M. & Mann, S., 2022, In: Angewandte Chemie - International Edition.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access23 Citations (Scopus) -
Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2
Gupta, K., Toelzer, C., Kavanagh Williamson, M., Shoemark, D. K., Oliveira, A., Davidson, A. D., Almuqrin, A. M., Staufer, O., Yadav Kadapalakere, S., Borucu, U., Garzoni, F., Fitzgerald, D. J., Spatz, J. P., Mulholland, A. J., Davidson, A. D., Berger-Schaffitzel, C. H. & Berger, I., 11 Jan 2022, In: Nature Communications. 13, 1, 12 p., 222.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile16 Citations (Scopus)135 Downloads (Pure) -
Structures of nonsense-mediated mRNA decay factors UPF3B and UPF3A in complex with UPF2 reveal molecular basis for competitive binding and for neurodevelopmental disorder-causing mutation.
Bufton, J. C., Powers, K. T., Toelzer, C., Berger, I., Berger-Schaffitzel, C. H. & Szeto, A., 31 May 2022, In: Nucleic Acids Research. 50, 10, p. 5934-5947 14 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile11 Citations (Scopus)87 Downloads (Pure) -
Synthetic and Biosynthetic Methods for Selective Cyclisations of 4,5-Epoxy Alcohols to Tetrahydropyrans
Bowen, J. I., Wang, L., Crump, M. P. & Willis, C. L., 14 Jan 2022, In: Organic and Biomolecular Chemistry. 20, 6, p. 1150-1175 26 p., 20.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile16 Citations (Scopus)65 Downloads (Pure) -
Synthetic virions reveal fatty acid-coupled adaptive immunogenicity of SARS-CoV-2 spike glycoprotein
Staufer, O., Gupta, K., Singh, G., Vasileiou, K., Berger-Schaffitzel, C. H., Platzman, I., Berger, I. & Spatz, J. P., 14 Feb 2022, (E-pub ahead of print) In: Nature Communications. 13, 1, 868 .Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile24 Citations (Scopus)131 Downloads (Pure) -
The Free Fatty Acid-Binding Pocket is a Conserved Hallmark in Pathogenic β-Coronavirus Spike Proteins from SARS-CoV to Omicron
Toelzer, C., Gupta, K., Yadav Kadapalakere, S., Hodgson, L. R., Kavanagh Williamson, M., Buzas, D., Borucu, U., Powers, K. T., Stenner, R. A., Vasileiou, K., Garzoni, F., Fitzgerald, D. J., Payré, C., Gautam, G., Lambeau, G., Davidson, A. D., Verkade, P., Martin, F., Berger, I. & Berger-Schaffitzel, C. H., 25 Nov 2022, In: Science Advances. 8, 47, 12 p., eadc9179.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile25 Citations (Scopus)101 Downloads (Pure)