Research Outputs
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Specifications of standards in systems and synthetic biology: status and developments in 2020
Schreiber, F., Sommer, B., Czauderna, T., Golebiewski, M., Gorochowski, T. E., Hucka, M., Keating, S. M., König, M., Myers, C., Nickerson, D. & Waltermath, D., 2020, In: Journal of Integrative Bioinformatics.Research output: Contribution to journal › Editorial (Academic Journal)
Open Access12 Citations (Scopus) -
Spontaneous membrane-less multi-compartmentalisation via aqueous two-phase separation in complex coacervate microdroplets
Moreau, N. G., Martin, N. C., Gobbo, P., Tang, T. D. & Mann, S., 28 Oct 2020, In: Chem. Commun.. 56, p. 12717-12720 5 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile39 Citations (Scopus)70 Downloads (Pure) -
Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide β-methyl branch incorporation
Nair, A. V., Robson, A., Ackrill, T. D., Till, M., Byrne, M. J., Back, C., Tiwari, K., Davies, J., Willis, C. L. & Race, P. R., 18 Sept 2020, (E-pub ahead of print) In: Scientific Reports. 10 (2020), 16 p., 15323.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile6 Citations (Scopus)142 Downloads (Pure) -
Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7-11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9
Bochel, A. J., Williams, C., McCoy, A. J., Hoppe, H.-J., Winter, A. J., Nicholls, R. D., Berger, I. & Crump, M. P., 1 Sept 2020, (E-pub ahead of print) In: Structure. 19 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile11 Citations (Scopus)110 Downloads (Pure) -
Synthetic biology open language (SBOL) version 3.0.0
Baig, H., Fontanarrosa, P., Kulkarni, V., McLaughlin, J. A., Vaidyanathan, P., Bartley, B., Beal, J., Crowther, M., Gorochowski, T. E., Grünberg, R., Misirli, G., Scott-Brown, J., Oberortner, E., Wipat, A. & Myers, C. J., 25 Jun 2020, In: Journal of Integrative Bioinformatics. 2020, 63 p., 20200017.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile5 Citations (Scopus)99 Downloads (Pure) -
Synthetic biology open language visual (SBOL visual) version 2.2
Baig, H., Fontanarrosa, P., Kulkarni, V., McLaughlin, J., Vaidyanathan, P., Bartley, B., Bhatia, S., Bhakta, S., Bissell, M., Clancy, K., Cox, R. S., Goñi Moreno, A., Gorochowski, T. E., Grunberg, R., Luna, A., Madsen, C., Misirli, G., Nguyen, T., Le Novere, N. & Palchick, Z. & 14 others, , 10 Jun 2020, In: Journal of Integrative Bioinformatics.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile15 Citations (Scopus)82 Downloads (Pure) -
Synthetic Virus-Derived Nanosystems (SVNs) for Delivery and Precision Docking of Large Multifunctional DNA Circuitry in Mammalian Cells
Aulicino, F., Capin, J. & Berger, I., 11 Aug 2020, In: pharmaceutics. 12, 8, 20 p., 759.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile15 Citations (Scopus)160 Downloads (Pure) -
Testing theoretical minimal genomes using whole-cell models
Rees-Garbutt, J. P., Rightmyer, J., Chalkley, O., Marucci, L. & Grierson, C. S., 10 Sept 2020, (Submitted) In: Genome Biology.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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The Bristol Sponge Microbiome Collection: A unique repository of deep-sea microorganisms and associated natural products
Williams, S., Stennett, H. L., Back, C., Tiwari, K., Ojeda Gomez, J., Challand, M. R., Hendry, K., Spencer, J., Essex-Lopresti, A., Willis, C. L., Curnow, P. & Race, P. R., 13 Aug 2020, In: Antibiotics. 9, 8, 189 p., 509.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile9 Citations (Scopus)179 Downloads (Pure) -
The extremophilic pharmacy: drug discovery at the limits of life
Stennett, H. L., Tiwari, K., Williams, S. E., Curnow, P. & Race, P. R., 26 Oct 2020, Biotechnological Applications of Extremophilic Microorganisms. Lee, N. M. (ed.). de Gruyter, p. 43-72 30 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book
Open AccessFile1 Citation (Scopus)18 Downloads (Pure) -
The SARS-CoV-2 spike protein: balancing stability and infectivity
Berger, I. & Schaffitzel, C., 2 Nov 2020, In: Cell Research. 2020, 2 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile68 Citations (Scopus)96 Downloads (Pure) -
The Synthetic Biology Open Language (SBOL) Version 3: Simplified Data Exchange for Bioengineering
McLaughlin, J. A., Beal, J., Misirli, G., Grünberg, R., Bartley, B. A., Scott-Brown, J., Vaidyanathan, P., Fontanarrosa, P., Oberortner, E., Wipat, A., Gorochowski, T. E. & Myers, C. J., 11 Sept 2020, In: Frontiers in Bioengineering and Biotechnology. 8, 15 p., 1009.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile39 Citations (Scopus)72 Downloads (Pure) -
Total Synthesis of Kalimantacin A
Davies, J. A., Bull, F. M., Walker, P. D., Weir, A. N. M., Lavigne, R., Masschelein, J., Simpson, T. J., Race, P. R., Crump, M. P. & Willis, C. L., 21 Aug 2020, In: Organic Letters. 22, 16, p. 6349-6353 5 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile5 Citations (Scopus)83 Downloads (Pure) -
Towards engineering biosystems with emergent collective functions
Gorochowski, T. E., Hauert, S., Kreft, J.-U., Marucci, L., Shatil, N. R., Tang, T.-Y. D., Bandiera, L., Bartoli, V., Dixon, D. O. R., Fedorec, A. J. H., Fellermann, H., Fletcher, A. G., Foster, T., Giuggioli, L., Matyjaszkiewicz, A., Mccormick, S. C., Montes Olivas, S. L., Naylor, J., Rubio Denniss, A. & Ward, D. T., 5 Jun 2020, (Accepted/In press) In: Frontiers in Bioengineering and Biotechnology.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Tunable genetic devices through simultaneous control of transcription and translation
Bartoli, V., Meaker, G., Di Bernardo, M. & Gorochowski, T. E., 29 Apr 2020, In: Nature Communications. 11, 11 p., 2095 (2020) .Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile31 Citations (Scopus)134 Downloads (Pure) -
Tutorial of numerical continuation and bifurcation theory for systems and synthetic biology
Blyth, M., Renson, L. & Marucci, L., 12 Aug 2020, (Unpublished) In: arXiv. 14 p.Research output: Contribution to journal › Article (Academic Journal)
File932 Downloads (Pure) -
Uncovering Biosynthetic Relationships Between Antifungal Nonadrides and Octadrides
De Mattos-Shipley, K. M. J., Spencer, C. E., Greco, C., Heard, D. M., O'Flynn, D. E., Dao, T. T., Song, Z., Mullholland, N. P., Vincent, J. L., Simpson, T. J., Cox, R. J., Bailey, A. M. & Willis, C. L., 7 Oct 2020, (E-pub ahead of print) In: Chemical Science. 11, p. 11570-11578 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile13 Citations (Scopus)96 Downloads (Pure) -
Unlocking the Therapeutic Potential of Antimicrobial Natural Products with Synthetic Biology
Rooms, L. D., Duke, P. W., Stach, J. E. M. & Race, P. R., 5 Oct 2020, In: International Biopharmaceutical Industry.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile203 Downloads (Pure) -
A biomimetic receptor for glucose
Tromans, R. A., Carter, T. S., Chabanne, L., Crump, M. P., Li, H., Matlock, J. V., Orchard, M. G. & Davis, A. P., Jan 2019, In: Nature Chemistry. 11, 1, p. 52-56 5 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile208 Citations (Scopus)1356 Downloads (Pure) -
Absolute quantification of translational regulation and burden using combined sequencing approaches
Gorochowski, T. E., Chelysheva, I., Eriksen, M., Nair, P., Pedersen, S. & Ignatova, Z., 3 May 2019, In: Molecular Systems Biology. 15, 5, p. e8719 15 p., e8719.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile48 Citations (Scopus)277 Downloads (Pure) -
Acoustic deformation for the extraction of mechanical properties of lipid vesicle populations
Silva, G. T., Tian, L., Franklin, A., Wang, X., Han, X., Mann, S. & Drinkwater, B. W., 24 Jun 2019, In: Physical Review E. 99, 6, 10 p., 063002.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile31 Citations (Scopus)493 Downloads (Pure) -
A high-resolution luminescent assay for rapid and continuous monitoring of protein translocation across biological membranes
De Castro Pereira, G., Allen, W., Watkins, D., Buddrus, L., Noone, D., Liu, X., Richardson, A., Collinson, I. & Chacinska, A., 5 Apr 2019, In: Journal of Molecular Biology. 431, 8, p. 1689-1699 11 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile34 Citations (Scopus)393 Downloads (Pure) -
A Modular Vaccine Platform Combining Self‐Assembled Peptide Cages and Immunogenic Peptides
Morris, C., Glennie, S., Lam, H., Baum, H., Kandage, D., Williams, N., Morgan, D., Woolfson, D. & Davidson, A., 21 Feb 2019, In: Advanced Functional Materials. 29, 8, 12 p., 1807357.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile40 Citations (Scopus)248 Downloads (Pure) -
A Natural Diels-Alder Biocatalyst Enables Efficient [4 + 2] Cycloaddition Under Harsh Reaction Conditions
Marsh, C. O., Lees, N. R., Han, L.-C., Byrne, M. J., Mbatha, S. Z., Maschio, L., Pagden-Ratcliffe, S., Duke, P., Stach, J. E. M., Curnow, P., Willis, C. L. & Race, P. R., 25 Aug 2019, (E-pub ahead of print) In: ChemCatChem. 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile7 Citations (Scopus)340 Downloads (Pure) -
An Esterase-like Lyase Catalyzes Acetate Elimination in Spirotetronate/Spirotetramate Biosynthesis
Lees, N. R., Han, L.-C., Byrne, M., Davies, J., Parnell, A., Moreland, P., Stach, J. E. M., Van der Kamp, M., Willis, C. & Race, P., 18 Feb 2019, In: Angewandte Chemie - International Edition. 58, 8, p. 2305-2309 5 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile10 Citations (Scopus)350 Downloads (Pure)