Research Outputs
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Antiproliferative and Antimigratory Effects of a Novel YAP-TEAD Interaction Inhibitor Identified Using in Silico Molecular Docking
Smith, S. A., Sessions, R. B., Shoemark, D. K., Williams, C., Ebrahimighaei, R., McNeill, M. C., Crump, M. P., McKay, T. R., Harris, G., Newby, A. C. & Bond, M., 14 Feb 2019, In: Journal of Medicinal Chemistry. 62, 3, p. 1291-1305 15 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile67 Citations (Scopus)808 Downloads (Pure) -
Arabidopsis immunity regulator EDS1 in a PAD4/SAG101-unbound form is a monomer with an inherently inactive conformation
Voss, M., Toelzer, C., Bhandari, D. D., Parker, J. E. & Niefind, K., 1 Dec 2019, In: Journal of Structural Biology. 208, 3, 107390.Research output: Contribution to journal › Article (Academic Journal) › peer-review
17 Citations (Scopus) -
Artificial morphogen-mediated differentiation in synthetic protocells
Tian, L., Li, M., Patil, A. J., Drinkwater, B. W. & Mann, S., 25 Jul 2019, In: Nature Communications. 10, 13 p., 3321 (2019).Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile79 Citations (Scopus)262 Downloads (Pure) -
A strategy for multicellular feedback control in mammalian cells
Postiglione, L., Wan, J., DI Bernardo, M. & Marucci, L., 1 Jun 2019, 2019 18th European Control Conference, ECC 2019. Institute of Electrical and Electronics Engineers (IEEE), p. 2669-2674 6 p. 8796200. (2019 18th European Control Conference, ECC 2019).Research output: Chapter in Book/Report/Conference proceeding › Conference Contribution (Conference Proceeding)
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A tunable dual-input system for on-demand dynamic gene expression regulation
Pedone, E., Postiglione, L., Aulicino, F., Rocca, D. L., Montes-Olivas, S., Khazim, M., di Bernardo, D., Pia Cosma, M. & Marucci, L., 2 Oct 2019, In: Nature Communications. 10, 13 p., 4481 (2019).Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile32 Citations (Scopus)166 Downloads (Pure) -
Augmented reality for the engineering of collective behaviours in microsystems
Rubio Denniss, A. M., Gorochowski, T. E. & Hauert, S., 5 Jul 2019, (E-pub ahead of print) 2019 IEEE International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS 2019). Institute of Electrical and Electronics Engineers (IEEE), 6 p.Research output: Chapter in Book/Report/Conference proceeding › Conference Contribution (Conference Proceeding)
Open AccessFile4 Citations (Scopus)177 Downloads (Pure) -
Bicyclic Boronate VNRX-5133 Inhibits Metallo- and Serine-β-Lactamases
Krajnc, A., Brem, J., Hinchliffe, P., Calvopina, K. A., Panduwawala, T. D., Lang, P., Kamps, J. J. A. G., Tyrrell, J. M., Widlake, E., Saward, B. G., Walsh, T. R., Spencer, J. & Schofield, C. J., 27 Aug 2019, In: Journal of Medicinal Chemistry. 62, 18, p. 8544-8556 13 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile160 Citations (Scopus)366 Downloads (Pure) -
Biodegradable Protein-Based Photoelectrochemical Cells with Biopolymer Composite Electrodes That Enable Recovery of Valuable Metals
Suresh, L., Vaghasiya, J., Jones, M. & Tan, S. C., 6 May 2019, In: ACS Sustainable Chemistry and Engineering. 7, 9, p. 8834-8841 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile24 Citations (Scopus)264 Downloads (Pure) -
Characterisation of the biosynthetic pathway to agnestins A and B reveals the reductive route to chrysophanol in fungi
Szwalbe, A. J., Williams, K., Song, Z., De Mattos-Shipley, K., Vincent, J. L., Bailey, A. M., Willis, C. L., Cox, R. J. & Simpson, T. J., 7 Jan 2019, In: Chemical Science. 10, 1, p. 233-238 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile46 Citations (Scopus)269 Downloads (Pure) -
Chemical communication in spatially organized protocell colonies and protocell/living cell micro-arrays
Wang, X., Tian, L., Du, H., Li, M., Mu, W., Drinkwater, B. W., Han, X. & Mann, S., 18 Sept 2019, (E-pub ahead of print) In: Chemical Science. 10, 41, p. 9446-9453 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile93 Citations (Scopus)132 Downloads (Pure) -
Cloning, Expression and Purification of Intact Polyketide Synthase Modules
Maschio, L., Parnell, A., Lees, N. R., Willis, C., Berger-Schaffitzel, C., Stach, J. E. M. & Race, P., 4 Feb 2019, (E-pub ahead of print) Methods in Enzymology: Metabolons and Supramolecular Enzyme Assemblies. Elsevier Inc., Vol. 617. p. 63-82 20 p. (Methods in Enzymology).Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book
5 Citations (Scopus) -
Communicating Structure and Function in Synthetic Biology Diagrams
Beal, J., Nguyen, T., Gorochowski, T., Goni-Moreno, A., Scott-Brown, J., McLaughlin, J., Madsen, C., Aleritsch, B., Bartley, B., Bhakta, S., Bissell, M., Castillo Hair, S., Clancy, K., Luna, A., Le Novere, N., Palchick, Z., Pocock, M., Sauro, H., Sexton, J. & Tabor, J. & 4 others, , 26 Jul 2019, In: ACS Synthetic Biology. 8, p. 1818-1825 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile28 Citations (Scopus)166 Downloads (Pure) -
Control of beta-Branching in Kalimantacin Biosynthesis: Application of 13C NMR to Polyketide Programming
Walker, P., Williams, C., Weir, A., Wang, L., Crosby, J., Race, P., Simpson, T., Willis, C. & Crump, M., 2 Sept 2019, In: Angewandte Chemie. 131, 36, p. 12576-12580 5 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile167 Downloads (Pure) -
CRISPR/Cas12a Multiplex Genome Editing of Saccharomyces cerevisiae and the Creation of Yeast Pixel Art
Ciurkot, K., Vonk, B., Gorochowski, T., Roubos, J. & Verwaal, R., 28 May 2019, In: Journal of Visualized Experiments. 147, 15 p., e59350.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile12 Citations (Scopus)449 Downloads (Pure) -
Designer artificial membrane binding proteins direct stem cells to the myocardium
Xiao, W., Green, T. I. P., Liang, X., Cuahtecontzi Delint, R., Perry, G., Roberts, M. S., Le Vay, K., Back, C., Ascione, R., Wang, H., Race, P. & Perriman, A., 3 Jul 2019, In: Chemical Science. 10, 32, p. 7610 - 7618 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile14 Citations (Scopus)205 Downloads (Pure) -
Designing minimalist membrane proteins
Curnow, P., 11 Oct 2019, In: Biochemical Society Transactions. p. 1233–1245 13 p.Research output: Contribution to journal › Book/Film/Article review (Academic Journal) › peer-review
Open AccessFile9 Citations (Scopus)203 Downloads (Pure) -
Directed Assembly of Homopentameric Cholera Toxin B-Subunit Proteins into Higher-Order Structures Using Coiled-Coil Appendages
Ross, J. F., Wildsmith, G. C., Johnson, M., Hurdiss, D. L., Hollingsworth, K., Thompson, R. F., Mosayebi, M., Trinh, C. H., Paci, E., Pearson, A. R., Webb, M. E. & Turnbull, W. B., 3 Apr 2019, In: Journal of the American Chemical Society. 141, 13, p. 5211-5219 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile17 Citations (Scopus)322 Downloads (Pure) -
DNA-based communication in populations of synthetic protocells
Joesaar, A., Yang, S., Bögels, B., van der Linden, A., Pieters, P., Kumar, B. V. V. S. P., Dalchau, N., Phillips, A., Mann, S. & de Greef, T. F. A., 1 Apr 2019, In: Nature Nanotechnology. 14, 4, p. 369-378 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile238 Citations (Scopus)166 Downloads (Pure) -
Emergence of a Thrombospondin Superfamily at the Origin of Metazoans
Shoemark, D., Ziegler, B., Watanabe, H., Strompen, J., Tucker, R. P., Ozbek, S. & Adams, J., 1 Jun 2019, In: Molecular Biology and Evolution. 36, 6, p. 1220-1238 19 p., msz060.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile6 Citations (Scopus)331 Downloads (Pure) -
Exact results for sheared polar active suspensions with variable liquid crystalline order
Loisy, A. G. L., Thompson, A., Eggers, J. & Liverpool, T. B., 14 Mar 2019, In: Journal of Chemical Physics. 150, 10, 5 p., 104902.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile3 Citations (Scopus)334 Downloads (Pure) -
Ex vivo culture of adult CD34+ stem cells using functional highly porous polymer scaffolds to establish biomimicry of the bone marrow niche
Severn, C. E., Eissa, A. M., Langford, C. R., Parker, A., Walker, M., Dobbe, J. G. G., Streekstra, G. J., Cameron, N. R. & Toye, A. M., 1 Dec 2019, In: Biomaterials. 225, 13 p., 119533.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile33 Citations (Scopus)374 Downloads (Pure) -
Guiding Biomolecular Interactions in Cells Using de Novo Protein - Protein Interfaces
Smith, A., Thomas, F., Shoemark, D., Woolfson, D. & Savery, N., 21 Jun 2019, In: ACS Synthetic Biology. 8, 6, p. 1284-1293 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile30 Citations (Scopus)183 Downloads (Pure) -
Hierarchical microfibrillar gels from evaporation-induced anisotropic self-assembly of in situ-generated nanocrystals
Wu, H., Zhang, Z., Mann, S. & Briscoe, W. H., 15 Dec 2019, In: Journal of Colloid and Interface Science. 558, p. 78-84 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile5 Citations (Scopus)97 Downloads (Pure) -
High-Performance UV Enhancer Molecules Coupled with Photosynthetic Proteins for Ultra-Low-Intensity UV Detection
Suresh, L., Vaghasiya, J., Nandakumar, D. K., Wu, T., Jones, M. & Tan, S. C., 11 Jul 2019, In: Chem. 5, 7, p. 1847-1860 14 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile30 Citations (Scopus)95 Downloads (Pure) -
Identification of the Initial Steps in Signal Transduction in the α4β2 Nicotinic Receptor: Insights from Equilibrium and Nonequilibrium Simulations
Oliveira, A. S. F., Shoemark, D. K., Campello, H. R., Wonnacott, S., Gallagher, T., Sessions, R. B. & Mulholland, A. J., 2 Jul 2019, In: Structure. 27, 7, p. 1171-1183.e3 17 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile19 Citations (Scopus)101 Downloads (Pure)