Research Outputs
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Enantioselective one-carbon expansion of aromatic rings by simultaneous formation and chromoselective irradiation of a transient coloured enolate
Saunthwal, R. K., Mortimer, J., Orr-Ewing, A. J. & Clayden, J., 25 Jan 2022, (E-pub ahead of print) In: Chemical Science. 13, 7, p. 2079-2085 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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Lithiation–borylation methodology in the total synthesis of natural products
Yeung, K., Mykura, R. C. & Aggarwal, V. K., 7 Feb 2022, (E-pub ahead of print) In: Nature Synthesis. 1, p. 117–126Research output: Contribution to journal › Article (Academic Journal) › peer-review
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Reversible Capture and Release of a Ligand Mediated by a Long-Range Relayed Polarity Switch in a Urea Oligomer
Wales, S. M., Morris, D. T. J. & Clayden, J., 10 Feb 2022, In: Journal of the American Chemical Society. 144, 7, p. 2841-2846 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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Sequential Photocatalytic Reactions for the Diastereoselective Synthesis of Cyclobutane Scaffolds
Deeprose, M. J., Lowe, M., Noble, A., Booker-milburn, K. I. & Aggarwal, V. K., 14 Jan 2022, In: Organic Letters. 24, 1, p. 137-141 5 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
1 Citation (Scopus) -
Strain‐Release‐Driven Friedel‐Crafts Spirocyclization of Azabicyclo[1.1.0]butanes
Tyler, J. L., Noble, A. & Aggarwal, V. K., 17 Jan 2022, In: Angewandte Chemie - International Edition. 61, 3, 7 p., e202114235.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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Synthesis of 2-deoxy mucin-type O-glycan analogues as biological probes
Johnson, S. E. & Galan, M. C., 9 Mar 2022, (E-pub ahead of print) In: Carbohydrate Research. 514, p. 108542 9 p., 108542.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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Synthetic and Biosynthetic Methods for Selective Cyclisations of 4,5-Epoxy Alcohols to Tetrahydropyrans
Bowen, J. I., Wang, L., Crump, M. P. & Willis, C. L., 14 Jan 2022, In: Organic and Biomolecular Chemistry. 20, 6, p. 1150-1175 26 p., 20.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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3D Printed Reactionware for Synthetic Electrochemistry with Hydrogen Fluoride Reagents
Heard, D. M., Doobary, S. & Lennox, A. J. J., 1 Jun 2021, In: ChemElectroChem. 8, 11, p. 2070-2074 5 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile5 Citations (Scopus)125 Downloads (Pure) -
Ambruticins: Tetrahydropyran Ring Formation and Total Synthesis
Willis, C. L., Bowen, J. I., Wang, L. & Crump, M. P., 28 Jun 2021, In: Organic and Biomolecular Chemistry. 19, 28, p. 6210-6215 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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A molecular communication channel consisting of a single reversible chain of hydrogen bonds in a conformationally flexible oligomer
Morris, D. T. J., Wales, S. M., Tilly, D. P., Farrar, E. H. E., Grayson, M. N., Ward, J. W. & Clayden, J., 9 Sep 2021, In: Chem. 7, 9, p. 2460-2472 13 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile2 Citations (Scopus)9 Downloads (Pure) -
Binding of l-kynurenine to X. campestris tryptophan 2,3-dioxygenase
Basran, J., Booth, E. S., Campbell, L. P., Thackray, S. J., Jesani, M. H., Clayden, J. P., Moody, P. C. E., Mowat, C. G., Raven, E. & Kwon, H., 1 Dec 2021, In: Journal of Inorganic Biochemistry. 225, 6 p., 111604.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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Direct Observation of Reactive Intermediates by Time-Resolved Spectroscopy Unravels the Mechanism of a Radical-Induced 1,2-Metalate Rearrangement
Lewis-Borrell, L. J., Sneha, M., Clark, I. P., Fasano, V., Noble, A., Aggarwal, V. K. & Orr-Ewing, A. J., 20 Oct 2021, In: Journal of the American Chemical Society. 143, 41, p. 17191 - 17199 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
1 Citation (Scopus) -
Fragment-linking peptide design yields a high-affinity ligand for microtubule-based transport
Cross, J. A., Chegkazi, M. S., Steiner, R. A., Woolfson, D. N. & Dodding, M. P., 16 Sep 2021, In: Cell Chemical Biology. 28, 9, p. 1347-1355.e5 15 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile2 Citations (Scopus)8 Downloads (Pure) -
Hydantoin-bridged medium ring scaffolds by migratory insertion of urea-tethered nitrile anions into aromatic C-N bonds
Millward, M. J., Ellis, E., Ward, J. W. & Clayden, J., 14 Feb 2021, In: Chemical Science. 12, 6, p. 2091-2096 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile3 Citations (Scopus)31 Downloads (Pure) -
Identifying palladium culprits in amine catalysis
Avanthay, M., Bedford, R. B., Begg, C. S., Böse, D., Clayden, J., Davis, S. A., Eloi, J. C., Goryunov, G. P., Hartung, I. V., Heeley, J., Khaikin, K. A., Kitching, M. O., Krieger, J., Kulyabin, P. S., Lennox, A. J. J., Nolla-Saltiel, R., Pridmore, N. E., Rowsell, B. J. S., Sparkes, H. A., Uborsky, D. V. & 3 others, , 2 Dec 2021, In: Nature Catalysis. 4, p. 994-998 5 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile1 Citation (Scopus)1 Downloads (Pure) -
Imide Condensation as a Strategy for the Synthesis of Core-diversified G-quadruplex Ligands with Anti-cancer and Anti-parasitic Activity
Street, S., Peñalver, P., O'Hagan, M., Hollingworth, G., Morales, J. C. & Galan, M. C., 17 May 2021, In: Chemistry - A European Journal. 27, 28, p. 7712-7721 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile1 Citation (Scopus)21 Downloads (Pure) -
Intramolecular Alkene Fluoroarylation of Phenolic Ethers Enabled by Electrochemically Generated Iodane
Lennox, A. J. J., Doobary, S. & Poole, D. L., 19 Nov 2021, In: Journal of Organic Chemistry. 86, 22, p. 16095-16103 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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Kinesin-1 captures RNA cargo in its adaptable coils
Cross, J. A. A., Woolfson, D. N. & Dodding, M. P., 1 Jul 2021, In: Genes and Development. 35, 13-14, p. 937-939 3 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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Molecular mechanism for kinesin-1 direct membrane recognition
Antón, Z., Weijman, J. F., Williams, C., Moody, E. R. R., Mantell, J., Yip, Y. Y., Cross, J. A., Williams, T. A., Steiner, R. A., Crump, M., Woolfson, D. N. & Dodding, M. P., 28 Jul 2021, In: Science Advances. 7, 31, 15 p., eabg6636.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile35 Downloads (Pure) -
Reverse Biomimetic’ Synthesis of L-Arogenate and its Stabilized Analogues from L-Tyrosine
Eagling, L., Leonard, D. J., Schwarz, M., Urruzuno, I., Boden, G. K., Wailes, J. S., Ward, J. W. & Clayden, J. P., 1 Sep 2021, In: Chemical Science. 12, 34, p. 11394-11398 5 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile1 Citation (Scopus)20 Downloads (Pure) -
Scalable synthesis and coupling of quaternary α-arylated amino acids: α-aryl substituents are tolerated in α-helical peptides
Leonard, D. J., Zieleniewski, F., Wellhöfer, I., Baker, E. G., Ward, J. W., Woolfson, D. N. & Clayden, J., 21 Jul 2021, In: Chemical Science. 12, 27, p. 9386-9390 5 p., 9386.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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Singlet and Triplet Contributions to the Excited-State Activities of Dihydrophenazine, Phenoxazine, and Phenothiazine Organocatalysts Used in Atom Transfer Radical Polymerization
Bhattacherjee, A., Sneha, M., Lewis-Borrell, L. J., Amoruso, G., Oliver, T. A. A., Tyler, J. L., Clark, I. P. & Orr-Ewing, A. J., 10 Mar 2021, In: Journal of the American Chemical Society. 143, 9, p. 3613 - 3627 15 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile10 Citations (Scopus)16 Downloads (Pure) -
Strain‐Release Driven Spirocyclization of Azabicyclo[1.1.0]butyl Ketones
Tyler, J. L., Noble, A. & Aggarwal, V. K., 17 May 2021, In: Angewandte Chemie - International Edition. 60, 21, p. 11824-11829 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile1 Citation (Scopus)24 Downloads (Pure) -
Studies on the lithiation, borylation, and 1,2‐metalate rearrangement of O‐cycloalkyl 2,4,6‐triisopropylbenzoates
Mykura, R. C., Songara, P., Luc, E., Rogers, J., Stammers, E. & Aggarwal, V. K., 3 May 2021, In: Angewandte Chemie - International Edition. 60, 20, p. 11436-11441 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile1 Citation (Scopus)27 Downloads (Pure) -
Synthesis of Dysoxylactam A Using Iterative Homologation of Boronic Esters
Rogers, J. J. & Aggarwal, V. K., Sep 2021, In: Asian Journal of Organic Chemistry. 10, 9, p. 2338-2341 4 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile24 Downloads (Pure)