Research Outputs
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Antibiotic Origami: Selective Formation of Spirotetronates in Abyssomicin Biosynthesis
Mbatha, S. Z., Back, C., Devine, A. J., Mulliner, H. M., Johns, S. T., Lewin, H., Cheung, K. A., Zorn, K., Stach, J. E. M., Hayes, M. A., Van der Kamp, M. W., Race, P. R. & Willis, C. L., 12 Aug 2024, (E-pub ahead of print) In: Chemical Science. 15, 34, p. 14009-14015 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Combining Total Synthesis and Genetic Engineering to Probe Dihydropyran Formation in Ambruticin Biosynthesis
Bowen, J. I., Zhong, X., Gao, K., Reed, B., Crump, M. P., Wang, L. & Willis, C. L., 12 Mar 2024, In: Chemical Science. 15, 14, p. 5319-5326 8 p., 5319.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
Anion-Dependent Hydrogen-Bond Polarity Switching in Ethylene-bridged Urea Oligomers
Tilly, D. P., Morris, D. T. J. & Clayden, J., 8 Nov 2023, In: Chemistry – A European Journal. 29, 62, 8 p., e202302210.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
Biosynthesis of pleuromutilin congeners using an Aspergillus oryzae expression platform
Alberti, F., Khairudin, K., Davies, J., Sangmalee, S., Willis, C. L., Foster, G. D. & Bailey, A. M., 15 Mar 2023, In: Chemical Science. 14, 14, p. 3826-3833 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access5 Citations (Scopus) -
Conformationally Controlled sp3‐Hydrocarbon‐Based α‐Helix Mimetics
Dewis, L. I., Madhavachary, R., Williams, C., Chiarparin, E., Myers, E. L., Butts, C. P. & Aggarwal, V. K., 24 May 2023, In: Angewandte Chemie - International Edition. 62, 23, e202301209.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access2 Citations (Scopus) -
Diphosphine Bioconjugates via Pt(0)-Catalyzed Hydrophosphination. A Versatile Chelator Platform for Technetium-99m and Rhenium-188 Radiolabeling of Biomolecules
Nuttall, R. E., Pham, T. T., Chadwick, A. C., Hungnes, I. N., Firth, G., Heckenast, M. A., Sparkes, H. A., Galan, M. C., Ma, M. T. & Pringle, P. G., 31 Jan 2023, (E-pub ahead of print) In: Inorganic Chemistry. 62, 50, p. 20582-20592 11 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access4 Citations (Scopus) -
Dynamic and Persistent Cyclochirality in Hydrogen-Bonded Derivatives of Medium-Ring Triamines
Morris, D. T. J., Wales, S. M., Echavarren, J., Zabka, M., Marsico, G., Ward, J. W., Pridmore, N. E. & Clayden, J., 18 Aug 2023, (E-pub ahead of print) In: Journal of the American Chemical Society. 145, 34, p. 19030-19041 12 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
Electrochemical synthesis of biaryls by reductive extrusion from N,N’-diarylureas
Stammers, E., Parsons, C. D., Clayden, J. & Lennox, A. J. J., 28 Jul 2023, In: Nature Communications. 14, 1, 4561.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access7 Citations (Scopus) -
Interrogating the Configurational Stability of Atropisomers
Heeb, J.-P., Clayden, J., Smith, M. & Armstrong, R. J., 4 Aug 2023, (E-pub ahead of print) In: Nature Protocols. 18, 9, p. 2745-2771 27 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile10 Citations (Scopus)206 Downloads (Pure) -
Interrogation of an Enzyme Library Reveals the Catalytic Plasticity of Naturally Evolved [4+2] Cyclases
Zorn, K., Back, C. R., Barringer, R., Chadimová, V., Manzo‐Ruiz, M., Mbatha, S. Z., Mobarec, J., Williams, S. E., Kamp, M. W. V. D., Race, P. R., Willis, C. L. & Hayes, M. A., 17 Jul 2023, In: ChemBioChem. 24, 14, e202300382.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access4 Citations (Scopus) -
Photoredox‐Catalyzed Decarboxylative Bromination, Chlorination and Thiocyanation Using Inorganic Salts
Wu, J., Shu, C., Li, Z., Noble, A. & Aggarwal, V. K., 14 Sept 2023, In: Angewandte Chemie - International Edition. 62, 38, e202309684.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access21 Citations (Scopus) -
Screw sense and screw sensibility: communicating information by conformational switching in helical oligomers
Morris, D. T. J. & Clayden, J., 16 Mar 2023, In: Chemical Society Reviews. 52, 7, p. 2480-2496 17 p.Research output: Contribution to journal › Review article (Academic Journal) › peer-review
Open Access9 Citations (Scopus) -
Switching imidazole reactivity by dynamic control of tautomer state in an allosteric foldamer
Tilly, D. P., Heeb, J. P., Webb, S. J. & Clayden, J., 8 May 2023, In: Nature Communications. 14, 1, 2647.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access14 Citations (Scopus) -
Synthesis and Applications of Bicyclo[1.1.0]butyl and Azabicyclo[1.1.0]butyl Organometallics
Tyler, J. & Aggarwal, V. K., 22 May 2023, In: Chemistry - A European Journal. 29, 29, e202300008.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access29 Citations (Scopus) -
Synthesis of Dihydropyridine Spirocycles by Semi-Pinacol-Driven Dearomatization of Pyridines
Abell, J. C., Bold, C. P., Vicens, L., Jentsch, T., Velasco, N., Tyler, J. L., Straker, R. N., Noble, A. & Aggarwal, V. K., 10 Jan 2023, (E-pub ahead of print) In: Organic Letters. 25, 2, p. 400-404 5 p.Research output: Contribution to journal › Letter (Academic Journal) › peer-review
Open AccessFile9 Citations (Scopus)86 Downloads (Pure) -
AuCl3-Catalyzed Hemiacetal Activation for the Stereoselective Synthesis of 2-Deoxy Trehalose Derivatives
Jeanneret, R., Walz, C., van Meerbeek, M., Coppock, S. & Galan, M. C., 2 Sept 2022, In: Organic Letters. 24, 34, p. 6304-6309 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile4 Citations (Scopus)107 Downloads (Pure) -
Automated stereocontrolled assembly-line synthesis of organic molecules
Fasano, V., Mykura, R. C., Fordham, J. M., Rogers, J. J., Banecki, B., Noble, A. & Aggarwal, V. K., 27 Oct 2022, (E-pub ahead of print) In: Nature Synthesis. 1, p. 902–907Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile22 Citations (Scopus)111 Downloads (Pure) -
Biocatalytic Enantioselective Synthesis of Atropisomers
Watts, O. F. B., Berreur, J., Collins, B. S. L. & Clayden, J., 6 Dec 2022, In: Accounts of Chemical Research. 55, 23, p. 3362-3375 14 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile32 Citations (Scopus)127 Downloads (Pure) -
De novo designed peptides for cellular delivery and subcellular localisation
Rhys, G. G., Cross, J. A., Dawson, W. M., Thompson, H. F., Shanmugaratnam, S., Savery, N. J., Dodding, M. P., Höcker, B. & Woolfson, D. N., 1 Sept 2022, In: Nature Chemical Biology. 18, 9, p. 999-1004 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile16 Citations (Scopus)259 Downloads (Pure) -
Enantioselective one-carbon expansion of aromatic rings by simultaneous formation and chromoselective irradiation of a transient coloured enolate
Saunthwal, R. K., Mortimer, J., Orr-Ewing, A. J. & Clayden, J., 25 Jan 2022, (E-pub ahead of print) In: Chemical Science. 13, 7, p. 2079-2085 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile5 Citations (Scopus)82 Downloads (Pure) -
Four‐Component Strain‐Release‐Driven Synthesis of Functionalized Azetidines
Tyler, J., Noble, A. & Aggarwal, V. K., 14 Dec 2022, In: Angewandte Chemie - International Edition. 61, 52, e202214049.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile17 Citations (Scopus)46 Downloads (Pure) -
Green Fluorescent Carbon Dots as Targeting Probes for LED-Dependent Bacterial Killing
Samphire, J. L., Takebayashi, Y., Hill, S. A., Hill, N., Heesom, K. J., Lewis, P. A., Alibhai, D. R., Spencer, J. & Galan, M. C., 1 Mar 2022, In: Nano Select. 3, 3, p. 662-672Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile138 Downloads (Pure) -
Lithiation–borylation methodology in the total synthesis of natural products
Yeung, K., Mykura, R. C. & Aggarwal, V. K., 7 Feb 2022, In: Nature Synthesis. 1, p. 117–126Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile44 Citations (Scopus)362 Downloads (Pure) -
Migratory Insertion of CO into a Au-C Bond
Cadge, J. A., Gates, P. J., Bower, J. F. & Russell, C. A., 2 Nov 2022, In: Journal of the American Chemical Society. 144, 43, p. 19719-19725 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile15 Citations (Scopus)114 Downloads (Pure) -
Molecular architecture of the autoinhibited kinesin-1 lambda particle
Weijman, J. F. M. S., Yadav Kadapalakere, S., Surridge, K. J., Cross, J. A. A., Mantell, J. M., Woolfson, D. N., Berger-Schaffitzel, C. H. & Dodding, M. P., 16 Sept 2022, In: Science Advances.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access8 Citations (Scopus)