Particle Size Anisotropy Analysis in Single Particle Tracking using the T-Matrix Method

Student thesis: Master's ThesisMaster of Science (MSc)

Abstract

This study is based on a developmental single nano-particle tracking technique
SaNTA whose purpose is to extract information regarding a particle's size anisotropy
including its size parameter and aspect ratio, from light scattering. The T-Matrix
method has been used to establish a computational model that calculates the scattered
light intensity and polarisation for a spheroidal particle undergoing Brownian
motion. The validity and limitation of this model has been tested. This study analysed
and simulated the relationship between particle orientation and scattered light
polarisation and intensity. It gives two potential solutions for achieving SaNTA's
goal - the autocorrelation function of the intensity signals detected by SaNTA and
the shape of the intensity scatter plot. It indicates that increasing the viscosity can
give more possibility for SaNTA to nd the particle's size anisotropy information.
Date of Award29 Sep 2020
Original languageEnglish
Awarding Institution
  • The University of Bristol
SupervisorHenkjan Gersen (Supervisor) & Simon Hanna (Supervisor)

Keywords

  • Single Particl Tracking
  • T-Matrix
  • Brownian Motion

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