The impact of insulin exposure on colorectal cancer metabolism

  • Aleksandra Ryk

Student thesis: Master's ThesisMaster of Science (MSc)


According to epidemiological data people with type 2 diabetes have a 50% increased risk of developing colorectal cancer. Hyperinsulinemia, which occurs in type 2 diabetes, is considered to be a factor linking these two diseases. One mechanism by which exposure to higher and more sustained levels of insulin might encourage tumourigenesis is by driving metabolic reprogramming in colorectal cells. As such, the aim of this investigation is to examine the impact of insulin exposure on metabolic reprogramming in colorectal tumour cells.
Date of Award28 Nov 2019
Original languageEnglish
Awarding Institution
  • The University of Bristol
SupervisorEmma E Vincent (Supervisor) & Ann C Williams (Supervisor)

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