According to epidemiological data people with type 2 diabetes have a 50% increased risk of developing colorectal cancer. Hyperinsulinemia, which occurs in type 2 diabetes, is considered to be a factor linking these two diseases. One mechanism by which exposure to higher and more sustained levels of insulin might encourage tumourigenesis is by driving metabolic reprogramming in colorectal cells. As such, the aim of this investigation is to examine the impact of insulin exposure on metabolic reprogramming in colorectal tumour cells.
| Date of Award | 28 Nov 2019 |
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| Original language | English |
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| Awarding Institution | |
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| Supervisor | Emma E Vincent (Supervisor) & Ann C Williams (Supervisor) |
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The impact of insulin exposure on colorectal cancer metabolism
Ryk, A. (Author). 28 Nov 2019
Student thesis: Master's Thesis › Master of Science by Research (MScR)