The Population Genetics and Heritability of Measures of Immune Function in Wild House Mice, Mus musculus domesticus

Abstract

The laboratory mouse, Mus musculus domesticus, is the workhorse of biological research, and have provided most of our understanding of the mammalian immune response. In contrast, the immune state and immunogenetics of wild animals have been hardly investigated at all. Here laboratory techniques have been applied to wild populations of house mice to determine the amount of genetic variation that exists among them, their population structure and whether genetic variation influences their immune responses.

Date of Award	28 Nov 2019
Original language	English
Awarding Institution	University of Bristol
Supervisor	Mark Viney (Supervisor) & Mark A Beaumont (Supervisor)