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Ethical considerations for choosing between possible models for using NIPD for aneuploidy detection

Research output: Contribution to journalArticle

Original languageEnglish
Pages (from-to)614-618
Number of pages5
JournalJournal of Medical Ethics
Volume38
Issue number10
Early online date28 Jun 2012
DOIs
DateAccepted/In press - 29 May 2012
DateE-pub ahead of print - 28 Jun 2012
DatePublished (current) - Oct 2012

Abstract

Recent scientific advances mean the widespread introduction of non-invasive prenatal diagnosis (NIPD) for chromosomal aneuploidies may be close at hand, raising the question of how NIPD should be introduced as part of antenatal care pathways for pregnant women. In this paper, the authors examine the ethical implications of three hypothetical models for using NIPD for aneuploidy in state-funded healthcare systems and assess which model is ethically preferable. In comparing the models, the authors consider their respective timings; how each model would fit with current screening and diagnostic tests offered to pregnant women; the implications of offering NIPD at different stages of pregnancy; and the potential for each model to support reproductive autonomy and informed decision-making. The authors conclude by favouring a model that would be offered at 11-13 weeks gestation, alongside existing combined screening, provided that this is accompanied by measures to maximise informed decision-making, for example, provision of adequate pretest and post-test counselling.

    Research areas

  • NONINVASIVE PRENATAL-DIAGNOSIS, FETAL-ABNORMALITY, DOWN-SYNDROME, CONSEQUENCES, PREECLAMPSIA, PREDICTION, WOMEN

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  • Full-text PDF (accepted author manuscript)

    Rights statement: This is the author accepted manuscript (AAM). The final published version (version of record) is available online via BMJ Publishing Group at http://dx.doi.org/10.1136/medethics-2011-100180.

    Accepted author manuscript, 182 KB, PDF document

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